With the disease burden of AIDS, tuberculosis, and malaria expected to make up less than 15 percent of the total disease burden in sub-Saharan Africa (SSA) by 2030, and non-communicable diseases to account for nearly 40 percent of the total in the region, “[a] revision of the approach to research and health care in SSA is therefore urgently needed, but international donors and health communities have generally been slow to respond to the changing environment,” Ole Olesen and M. Iqbal Parker of the International Centre for Genetic Engineering and Biotechnology in South Africa write in a commentary in Tropical Medicine & International Health. “Private and public funding for health research in Africa remains therefore disproportionately focused on the three major infectious diseases, whereas only smaller amounts have been allocated to confront other diseases,” they write and provide examples.
Neglected Tropical Diseases (NTDs)
“Chagas disease, a parasitic infection spread to humans by insects, is not the new HIV/AIDS of the Americas, according to infectious disease experts who called the comparison,” made in an editorial published in PLoS Neglected Tropical Diseases last week, “‘unrealistic’ and ‘unfortunate,'” ABC News’ “Medical Unit” blog reports. “Rick Tarleton, president of the Chagas Disease Foundation, said the diseases have little in common beyond disproportionately affecting poor people,” the blog notes (Moisse, 6/1).
Ghana “will contribute about $1 million towards the prevention and control of endemic neglected tropical diseases (NTDs) in order to protect the gains made by the country in Guinea worm eradication and the elimination of trachoma,” the country’s health minister announced on Monday at the opening of a Regional Stakeholders’ Consultative Meeting on NTDs, PANA/AfriqueJet reports. Health Minister Albin Bagbin “also called on African countries to support interventions to address NTDs and improve coordination among all stakeholders in implementing NTD programs,” the news agency writes.
“In order to break the vicious cycle that leaves tropical diseases neglected, existing programs that diagnose and treat patients need to be expanded and medical research to develop simpler, more effective tools needs to be supported, according to a new report, Fighting Neglect [.pdf], released [Monday] by Medecins Sans Frontieres/Doctors Without Borders (MSF),” the organization reports on its webpage. “Charting the organization’s 25 years of experience in diagnosing and treating Chagas disease, sleeping sickness, and kala azar in Latin America, sub-Saharan Africa, South Asia and the Caucasus, the report examines past, present, and future management of the diseases and notes that access to quality life-saving treatment requires much greater political will among major international donors and national governments of endemic countries,” MSF writes (6/11).
Agence France-Presse reports on human African trypanosomiasis, “commonly known as sleeping sickness, which is transmitted by tsetse flies found in 36 sub-Saharan African countries,” writing, “Without treatment in four months to a year, ‘the parasite penetrates into the brain, causing serious neurological symptoms, until death,’ said Doctor Benedict Blaynay, head of neglected tropical diseases at French pharmaceutical giant Sanofi.” The news service highlights efforts to control the disease in Chad, noting, “For the people living in Chad’s rural communities, the strange symptoms of sleeping sickness have long been shrouded in superstition about witchcraft and demonic possession. But the World Health Organization says it is not a losing battle.”
“Brazilian researchers say they have successfully tested a vaccine against schistosomiasis, a disease caused by parasitic worms that afflicts more than 200 million people worldwide,” Agence France-Presse reports. Researchers from the Oswaldo Cruz Institute in Rio de Janeiro “said it had successfully tested the vaccine in humans, but that more testing would be required in areas where the parasite is most common, mainly in Africa and South America,” the news agency writes. Institute researcher Tania Araujo-Jorge said she hopes the vaccine will be available for distribution within three years, according to AFP (6/13).
“Researchers are warning that the little-known Chagas disease could pose a threat similar to other global pandemics,” Fox News reports, noting Chagas disease “is a parasitic illness that is most commonly transmitted by the so-called ‘kissing bugs,’ a subfamily of blood-sucking insects, through the parasite called Trypanosoma cruzi” (5/31). In an editorial published in PLoS Neglected Tropical Diseases on Tuesday, a team of experts in tropical diseases from Baylor College of Medicine in Texas “likens some aspects of the disease to HIV, the virus that causes AIDS, and warns of a possible pandemic,” GlobalPost writes (Wolfe, 5/31).
“The Intellectual Property & Science division of Thomson Reuters [on Tuesday] announced the publication of a new study tracking the current status of research on neglected tropical diseases [NTDs],” a Thomson Reuters Corporation press release reports. “The Global Research Report Neglected Tropical Diseases analyzes research output across countries and fields from 1992-2011 and finds a two-fold increase in published literature focused on a group of diseases identified by the World Health Organization as underserved by public health services,” the press release states, adding, “Despite these recent gains, the total research output is still significantly less than that of ‘first world’ diseases” (6/19).
The END7 campaign, a global advocacy campaign run by the Global Network for Neglected Tropical Diseases (NTDs) “to raise awareness of the seven most common NTDs and cultivate the resources necessary to end them by 2020,” is launching a tweet chat series on Twitter, which aims to bring global health non-governmental organizations together “to ask questions and share tips on social media,” a post in the Global Network’s “End the Neglect” blog reports. “We’ll have a special guest for each session and a topic of conversation,” the blog notes, adding, “Our first series is Thursday, June 14th at 2:00 EST and features Mo Scarpelli,” a Brooklyn-based filmmaker and multimedia producer, who will “help us discuss how to use multimedia for effective storytelling” (Patel, 6/13).
As the BRIC countries — Brazil, Russia, India, and China — invest more in innovations in health technologies and other areas, “many are looking to these countries to correct the global health research and development (R&D) imbalance that leaves the poor without needed products such as an improved tuberculosis (TB) vaccine or tests to help diagnose patients in remote rural settings,” David de Ferranti, president of Results for Development Institute (R4D), writes in the Huffington Post Blog. Writing that “India, which has already played such an important role in manufacturing affordable antiretroviral drugs, vaccines, and other essential health commodities for developing countries,” de Ferranti asks whether India “is … ready to play a leading role in health R&D?”