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Single-Dose Of Experimental Malaria Drug Clears Parasites In Mice, Represents Potential New Class Of Drugs To Treat Malaria In Humans

An experimental malaria drug was shown to effectively treat the disease in mice with only a single dose, according to a study published Thursday in the journal Science, Reuters reports (Kelland, 9/2). The new drug, known as NITD609, “represents an entirely new class of medicines to treat malaria … Human trials, backed by Swiss pharmaceutical giant Novartis AG, could begin later this year,” the Wall Street Journal writes (Naik, 9/3).

Recent Releases In Global Health

Several blogs, publications examine the U.N. Millennium Development Goals (MDGs) summit: The MDGs serve a dual purpose “helping the poor countries to fight poverty and the rich countries to preserve a sense of social solidarity,” writes Jeffrey Sachs, director of Columbia University’s Earth Institute in a post on the Guardian’s…

Opinions: MDG Progress; Drug Patents; Aid For Scientific Research; Avoiding Food Crises; Hunger In India; U.S. Commitments To PEPFAR, Global Fund

MDGs Are Less About Timeline, More About Identifiable Progress “Between the catastrophes of the Haiti earthquake and the Pakistan floods, there was actually some good news this spring on the global health front, which offers hope that the United Nations’ ambitious Millennium Development Goals might not be at a standstill.…

Study Examines Movement Of Pediatric Drug Testing Outside The U.S.

“A law intended to speed up development of new drugs for U.S. kids has ended up financing clinical trials in poor countries, where the medicines might never become available,” suggest the authors of a study published online Monday in the journal Pedatrics, Reuters reports (Joelving, 8/23).

Recent Releases In Global Health

Lancet Infectious Diseases Reflects On TB Diagnosis In Children “[N]ew diagnostic techniques [for tuberculosis] need to be studied in children,” according to a Lancet Infectious Diseases Reflection. “Tuberculosis is an important cause of morbidity and mortality in children worldwide, but estimates of disease burden are inaccurate because most cases are…

Mathematical Model Projects Potential Impact Of Current Tools Fighting Malaria In Africa

Current tools for combating malaria, such as artemisinin-combination therapy (ACT) and increasing coverage of insecticide-treated bednets (ITN) “could dramatically reduce the burden of malignant malaria on parts of Africa if a comprehensive, sustained intervention programme were in place,” according to a study published this week in PLoS Medicine, CORDIS News reports.
“According to the study, half of the world’s population is at risk of malaria infection, and every year it claims the lives of nearly 1 million people in sub-Saharan Africa,” the news service adds. “Plasmodium falciparum, one of the species of Plasmodium that causes malaria in humans, is transmitted by Anopheles mosquitoes that normally bite (and inject the deadly parasites) at night,” CORDIS News reports (8/11).