“In dengue-endemic areas such as South-East Asia, in contrast to conventional thinking, rural areas rather than cities may bear the highest burden of dengue fever,” according to a study led by Wolf-Peter Schmidt from the Nagasaki Institute of Tropical Medicine in Japan and published in this week’s PLoS Medicine, a PLoS press release states. The authors “analyzed a population in Kanh-Hoa Province in south-central Vietnam (~350,000 people) that was affected by two dengue epidemics between January 2005 and June 2008” and “found that at low human population densities, mostly in rural areas, dengue risk is up to three times higher than in cities, presumably because the number of mosquitoes per individual is higher in low-density areas,” according to the release (8/30).