Table 1: Measures of Spending and Use of Insulin Products in Medicare Part D, 2007-2017
Number of Part D enrollees using insulin
(in millions)
Total number of insulin prescriptions (in millions) Total Part D spending on insulin (in billions) Average per capita total Part D spending on insulin1
Total out-of-pocket spending on insulin by non-LIS enrollees2
(in millions)
Average out-of-pocket spending on insulin by non-LIS enrollees2
2007 1.6 14.8 $1.4 $862 $210.1 $324
2008 1.8 16.9 $1.9 $1,059 $269.9 $368
2009 1.9 18.6 $2.4 $1,246 $324.7 $404
2010 2.1 20.1 $2.9 $1,424 $384.9 $447
2011 2.2 22.2 $3.7 $1,651 $367.3 $386
2012 2.4 24.5 $4.8 $1,972 $466.1 $429
2013 2.7 28.1 $6.6 $2,411 $599.5 $447
2014 2.9 30.1 $9.0 $3,116 $735.9 $513
2015 3.0 31.8 $11.0 $3,681 $857.4 $572
2016 3.1 33.3 $12.1 $3,949 $911.5 $588
2017 n/a n/a $13.3 n/a n/a n/a
NOTE: n/a indicates data not available. Total spending does not account for rebates; includes Medicare, plan, and beneficiary out-of-pocket payments. Number of prescriptions is standardized to a 30-day supply. 1Among all enrollees using insulin. 2Among non-LIS enrollees using insulin.
SOURCE: KFF analysis of 2007-2016 prescription drug event claims data from a 5% sample of Medicare beneficiaries from the Centers for Medicare & Medicaid Services (CMS) Chronic Conditions Data Warehouse, and 2017 data from the CMS Medicare Part D Drug Spending Dashboard.
Table 2: Medicare Part D Spending on Insulin Products, 2013-2017
Average Spending Per Dosage Unit (Weighted) Average Spending Per Claim
Drug name Number of users in 2017 First year of data1 First year 2016 2017 Change, 2016-2017 CAGR, first year-2017 2016 2017 Change, 2016-2017
Afrezza 639 2016 $2.91 $2.91 $3.54 21.6% 21.6% $566 $690 $124
Apidra 3,489 2013 $12.35 $23.94 $25.02 4.5% 19.3% $636 $713 $77
Apidra Solostar 7,740 2013 $16.06 $30.81 $32.16 4.4% 18.9% $726 $759 $32
Humalog 283,221 2013 $14.43 $23.74 $25.73 8.4% 15.5% $452 $488 $36
Humalog Kwikpen
U-100
414,797 2013 $18.71 $30.77 $33.54 9.0% 15.7% $661 $720 $59
Humalog Kwikpen
U-200
23,598 2015 $57.96 $62.64 $67.97 8.5% 8.3% $1,036 $1,134 $98
Humalog Mix 50-50 3,089 2013 $15.08 $25.51 $27.93 9.5% 16.7% $825 $898 $73
Humalog Mix 50-50 Kwikpen 5,730 2013 $18.93 $31.06 $33.85 9.0% 15.6% $1,020 $1,122 $103
Humalog Mix 75-25 33,042 2013 $14.91 $25.22 $27.57 9.3% 16.6% $671 $744 $73
Humalog Mix 75-25 Kwikpen 67,462 2013 $18.74 $30.87 $33.74 9.3% 15.8% $851 $957 $106
Humulin 70-30 89,109 2013 $7.56 $11.98 $12.82 7.0% 14.1% $342 $374 $31
Humulin 70/30 Kwikpen 25,412 2014 $20.50 $26.22 $27.04 3.2% 9.7% $691 $739 $48
Humulin N 131,313 2013 $5.69 $7.79 $7.95 2.1% 8.7% $237 $255 $18
Humulin N Kwikpen 27,261 2014 $18.84 $22.11 $20.46 -7.5% 2.8% $529 $509 -$20
Humulin R 102,072 2013 $6.54 $9.47 $9.74 2.9% 10.5% $180 $193 $13
Humulin R U-500 14,547 2013 $39.90 $63.96 $70.65 10.4% 15.4% $1,838 $1,990 $153
Humulin R U-500 Kwikpen 13,153 2016 $86.90 $86.90 $91.14 4.9% 4.9% $1,461 $1,533 $72
Lantus 614,743 2013 $15.31 $24.88 $24.95 0.3% 13.0% $469 $477 $8
Lantus Solostar 1,112,315 2013 $17.09 $24.60 $24.82 0.9% 9.8% $502 $503 $0
Levemir 188,078 2013 $15.56 $27.23 $27.29 0.2% 15.1% $491 $499 $7
Levemir Flextouch 509,282 2014 $23.55 $26.79 $26.85 0.2% 4.5% $557 $564 $6
Novolin 70-30 113,491 2013 $7.12 $10.25 $10.46 2.0% 10.1% $276 $298 $22
Novolin N 78,553 2013 $7.00 $9.86 $10.15 3.0% 9.7% $224 $244 $20
Novolin R 90,692 2013 $7.92 $11.69 $11.77 0.7% 10.4% $173 $188 $16
Novolog 285,494 2013 $15.21 $25.01 $27.68 10.7% 16.2% $471 $548 $77
Novolog Flexpen 546,717 2013 $19.18 $31.74 $35.23 11.0% 16.4% $617 $701 $84
Novolog Mix 70-30 42,341 2013 $15.55 $25.63 $28.43 10.9% 16.3% $653 $758 $106
Novolog Mix 70-30 Flexpen 96,569 2013 $19.08 $31.52 $35.05 11.2% 16.4% $853 $971 $118
Toujeo Solostar 190,489 2015 $74.20 $73.94 $75.17 1.7% 0.6% $556 $580 $24
Tresiba Flextouch
U-100
63,235 2015 $28.63 $29.57 $29.79 0.8% 2.0% $499 $512 $12
Tresiba Flextouch
U-200
89,703 2015 $58.36 $59.03 $59.22 0.3% 0.7% $847 $880 $33
NOTE: CAGR is compound annual growth rate. 1For insulin products that were not yet available in 2013, the first year that they appear in the Part D dashboard is used as the first year for purposes of measuring change in spending per dosage unit.
SOURCE: Centers for Medicare & Medicaid Services, Medicare Part D Drug Spending Dashboard, March 2019 update 2013-2017 data).
Table 3: Out-of-Pocket Spending by Non-Low Income Subsidy (LIS) Medicare Part D Enrollees on Insulin Products, 2007-2016
Average out-of-pocket spending by non-LIS insulin users Percent change in out-of-pocket spending by
non-LIS insulin users
Drug name First year of Part D data1 First year 2015 2016 First year-2016 2015-2016 Annual growth
rate, first
year-2016
All non-LIS insulin users 2007 $324 $572 $588 81% 3% 7%
Afrezza 2015 $153 $153 $226 48% 48% 48%
Apidra 2007 $213 $381 $373 75% -2% 6%
Apidra Solostar 2009 $131 $345 $354 170% 3% 15%
Humalog 2007 $226 $318 $354 56% 11% 5%
Humalog Kwikpen U-100 2015 $328 $328 $358 9% 9% 9%
Humalog Kwikpen U-200 2015 $105 $105 $339 222% 222% 222%
Humalog Mix 50-50 2007 $298 $556 $627 110% 13% 9%
Humalog Mix 50-50 Kwikpen 2015 $456 $456 $455 0% 0% 0%
Humalog Mix 75-25 2007 $394 $462 $545 38% 18% 4%
Humalog Mix 75-25 Kwikpen 2015 $508 $508 $546 7% 7% 7%
Humulin 70/30 Kwikpen 2014 $343 $431 $481 40% 12% 18%
Humulin 70-30 2007 $228 $301 $326 43% 9% 4%
Humulin N 2007 $204 $156 $183 -10% 17% -1%
Humulin N Kwikpen 2014 $234 $336 $337 44% 0% 20%
Humulin R 2007 $109 $115 $140 29% 22% 3%
Humulin R U-500 2015 $798 $798 $822 3% 3% 3%
Humulin R U-500 Kwikpen 2016 $344 n/a $344 n/a n/a n/a
Lantus 2007 $245 $450 $434 77% -4% 7%
Lantus Solostar 2007 $106 $420 $413 291% -2% 16%
Levemir 2007 $203 $405 $414 104% 2% 8%
Levemir Flexpen 2012 $305 $132 $110 -64% -17% -22%
Levemir Flextouch 2014 $145 $429 $448 209% 5% 76%
Novolin 70-30 2007 $176 $285 $272 55% -5% 5%
Novolin N 2007 $121 $234 $223 85% -4% 7%
Novolin R 2007 $70 $161 $156 123% -3% 9%
Novolog 2007 $192 $325 $342 78% 5% 7%
Novolog Flexpen 2012 $245 $316 $346 42% 10% 9%
Novolog Mix 70-30 2007 $322 $412 $431 34% 5% 3%
Novolog Mix 70-30 Flexpen 2012 $397 $509 $555 40% 9% 9%
Toujeo Solostar 2015 $177 $177 $359 103% 103% 103%
Tresiba Flextouch U-100 2016 $220 n/a $220 n/a n/a n/a
Tresiba Flextouch U-200 2016 $313 n/a $313 n/a n/a n/a
NOTE: LIS is low-income subsidy. n/a indicates data not available. 1For insulin products that were not yet available in 2007, the first year that they appear in the Part D claims data is used as the first year for purposes of measuring change in out-of-pocket spending.
SOURCE: KFF analysis of 2007-2016 prescription drug event claims data from a 5% sample of Medicare beneficiaries from the Centers for Medicare & Medicaid Services (CMS) Chronic Conditions Data Warehouse.

 

Data Note

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