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AIDS 2010: Understanding HIV Transmission Mechanisms: Microbicides and PrEP

AIDS 2010: Understanding HIV Transmission Mechanisms: Microbicides and PrEP

For more information on this session, including access to speaker presentations, please see the conference Programme-at-a-Glance.

Understanding factors and mechanisms, cellular pathways, viral features and immune interaction of mucosal HIV transmission should provide important insight to design prevention methods to interrupt transmission. Animal and human studies aiming at blocking mucosal HIV transmission including microbicides and pre-exposure prophylaxis (PrEP) are ongoing. Outcomes of such studies may reshape the landscape of HIV prevention programmes. One of the most promising prevention technologies currently in trials are microbicides which contain antiretrovirals (also referred to as topical PrEP) and oral antiretroviral PrEP or a combination of both. Results of microbicides/PrEP trials are likely to begin appearing in late 2010 and early 2011. Research and development of novel prevention technologies should take into account ethical considerations and involvement of communities in study design. The session will also address challenges and limitations encountered during clinical trials from a community perspective.

Event Date

Jul 22, 2010