The goal of an “AIDS-free generation” “requires an ambitious implementation-science agenda that improves efficiency and effectiveness and incorporates strategies for overcoming the stigma and discrimination that continue to limit the uptake and utilization of [treatment, prevention and care] services,” AIDS 2012 Co-Chair Diane Havlir of the University of California-San Francisco School of Medicine and Chris Beyrer of the Johns Hopkins Center for AIDS Research write in a New England Journal of Medicine opinion piece. They note that “[r]esearch efforts on HIV vaccines will also probably be key, and the field has been reinvigorated” by recent study results. “A combination approach to prevention that includes HIV treatment can generate tremendous gains in the short term by curtailing new HIV infections, but ending the AIDS epidemic will probably require a vaccine, a cure, or both,” they write.
“Gunmen in Pakistan shot and wounded a staff member of the World Health Organization (WHO) and an expatriate consultant working for the United Nations health agency on Tuesday, the WHO said,” Reuters reports (Nebehay, 7/17). “The attack was a further blow to the three-day polio vaccination drive, which had already been stymied in some parts of the country by Taliban threats. Attacks on international aid workers in Karachi have been rare,” according to the New York Times (Walsh, 7/17). WHO said in a statement there was “no evidence to suggest that this was a deliberate or targeted attack against polio eradication efforts or WHO,” Agence France-Presse notes (Mansoor, 7/16). BBC News writes, “No group has said it carried out the shooting, but the Taliban have issued threats against the polio drive” (7/17). “A ban on polio vaccinations imposed by the Taliban could affect about 280,000 children living in tribal areas of northwest Pakistan, according to estimates from the [WHO],” CNN reports (Park, 7/17).
In this post on her blog, “The Garrett Update,” Laurie Garrett, senior fellow for global health at the Council on Foreign Relations (CFR), examines the potential implications of a fake hepatitis vaccine campaign carried out by the CIA in Pakistan last year in an attempt to gather DNA from Osama bin Laden’s family. She writes that “the fake vaccine effort has now put at least 300,000 children in Afghanistan and Pakistan in danger of contracting polio, led multiple imams and Taliban leaders to declare vaccines are CIA plots, and [on Tuesday] prompted what appears to have been an assassination attempt against a World Health Organization immunization convoy, leaving two individuals alive, but shot” (7/17).
NPR’s “Shots” blog reports on the results of a “high-visibility pilot project to vaccinate 100,000 Haitians against cholera.” The blog writes, “Almost 90 percent of the target population — half in Port-au-Prince and the other half in a remote rural area — got fully protected against cholera, meaning they got two doses of the oral vaccine,” adding, “The sponsors of the project — the nonprofit medical groups GHESKIO in Port-au-Prince and Partners in Health in rural Haiti — presented the results on Monday at a session with the country’s health minister, Dr. Florence Guillaume.”
Pakistan Polio Immunization Campaign Might Not Reach 240,000 Children Because Of Militant Leaders' Bans On Vaccine
A national polio vaccination campaign set to begin this week in Pakistan might not reach 240,000 children in the northwest because of a Taliban ban on the inoculations, Agence France-Presse reports. Local militant leaders “have banned polio vaccinations in the northwestern tribal region of Waziristan to protest against U.S. drone attacks” and “have condemned the immunization campaign, which is slated to begin on Monday, as a cover for espionage,” the news agency writes (7/14). The social affairs secretary for the country’s Federally Administered Tribal Areas “says local officials and non-governmental organizations are working with tribal elders and clerics to help convince the Taliban and other militant groups to allow the immunization campaign to take place in North and South Waziristan,” according to VOA News’ “Breaking News” blog (7/13). TIME reports that the leaders have said the ban on vaccinations “would not be lifted until the drone strikes stop” (Baker, 7/15).
“A cure for AIDS remains a distant prospect but a host of drug treatments and other advances have fueled fresh hope that new [HIV] infections may someday be halted for good,” Agence France-Presse reports. “Strategies for ending the 30-year AIDS epidemic through advances in treatment, testing and prevention are high on the agenda of” the XIX International AIDS Conference, “when it returns to the United States next week after two decades,” according to the news agency (Sheridan, 7/14). “Thanks to drugs that can control the virus for decades, AIDS is no longer a death sentence,” Reuters writes in an article examining AIDS vaccine research. “New infections have fallen by 21 percent since the peak of the pandemic in 1997 and advances in prevention — through voluntary circumcision programs, prevention of mother-to-child transmission and early treatment — promise to cut that rate even more,” the news service states (Steenhuysen, 7/15).
UNICEF and the WHO “are warning of an alarming upsurge in cholera across West Africa’s Sahel region, the area at the southern fringe of the Sahara Desert running from Mauritania to Chad,” VOA News reports (Schlein, 7/10). “So far in 2012, cholera has killed nearly 700 people in West and Central Africa and more than 29,000 cases were reported,” according to a UNICEF press release (7/10). “Both UNICEF and WHO say they are critically short of funds to do what is needed to contain the outbreak,” but “[t]hey say action must be taken now before the number of cholera cases explodes,” VOA writes (7/10). IRIN examines efforts to curb the spread of cholera in Guinea, with the administration of a vaccine, and Sierra Leone (7/10).
New York Times Examines How CIA's Decision To Use Vaccination Team Affecting Polio Eradication Efforts
The New York Times examines how the CIA’s 2011 decision to use a vaccination team to collect DNA samples and information from residents of Osama bin Laden’s compound damaged efforts to vaccinate children for polio in Pakistan. The effects of the campaign, which has prompted local leaders to ban polio vaccination teams, will not be fully known “until the summer spike of polio cases tapers off in the fall,” the newspaper writes and reviews the history of the case as well as polio in the region. Elias Durry, the WHO’s polio coordinator for Pakistan, “and other leaders of the global war on polio say they have recovered from worse setbacks,” and many experts are confident that Pakistan eventually will eliminate polio, according to the New York Times (McNeil, 7/9).
Gates Foundation Plans To Invest In Biotech Companies To Improve Global Access To Treatments, Vaccines For Infectious Diseases
The Bill & Melinda Gates Foundation “plans to take equity stakes in up to a dozen biotech companies this year, signaling a shift towards a ‘venture capital’ approach at the world’s biggest philanthropic organization” and “mark[ing] a further move away from its traditional approach of grant-giving and towards a more business-oriented way to support the development of treatments and vaccines for infectious diseases affecting the world’s poor,” the Financial Times reports. Trevor Mundel, president of the Gates Foundation’s Global Health Program, said the foundation will make a series of investments worth several million dollars each “and not ask for a return but for global access. … We will specify the countries and the diseases,” according to the newspaper. The Financial Times notes that “[t]he move points to growing interest in working directly with companies rather than primarily through co-operating via non-profit ‘product development partnerships’ or intermediaries such as the Medicines for Malaria Venture and the Tuberculosis Alliance” (Jack, 6/26).
“Research funded by the Dengue Vaccine Initiative (DVI) involving an economic analysis of producing a tetravalent dengue vaccine shows that the cost could be as low as $0.20 per dose with an annual production level of 60 million doses packaged in 10-dose vials,” a Sabin Vaccine Institute press release reports. The study, published in the July 6 issue of the journal Vaccine, “used data on a vaccine developed by U.S. NIH and the facilities of the Instituto Butantan in Sao Paulo, Brazil,” the press release notes, adding the findings “should provide confidence to ministries of health that they can aggressively plan for the inclusion of dengue vaccine in their immunization programs, as the vaccine should be available at a cost that even middle-income and developing countries can afford” (6/27).