Nature reports how “[i]n the hunt for drugs that target diseases in the developing world, … [p]harmaceutical companies are making entire libraries of chemical compounds publicly available, allowing researchers to rifle through them for promising drug candidates.” The journal writes, “The latest push for open innovation, unveiled last month as part of a World Health Organization road map to control neglected tropical diseases, will see 11 companies sharing their intellectual property to give researchers around the world a head start on investigating drug leads.”
Pakistan and Afghanistan, “the world’s two worst polio-affected countries,” have “decided to form a joint block under the World Health Organization to eradicate the infectious disease — which causes motor paralysis and the atrophy of skeletal muscles, often resulting in permanent physical disability or deformity — by December 2012,” Inter Press Service reports. “The decision was made last year by the Technical Advisory Board (TAG), which is responsible for developing new strategies to wipe out the disease globally,” the news service notes.
“The key to India’s success” in going a full year without recording a case of polio “was to take ownership of the problem and the solution, allowing for locals to learn from the expertise of the international community while not becoming dependent” on non-governmental organizations (NGOs) and international donors, William Thomson, a research assistant at the U.S. Naval War College, writes in The Diplomat’s “India Decade.”
In this video report, Al Jazeera examines polio eradication efforts in Pakistan, writing, “[I]n an unusual effort to eliminate the disease, health workers are stopping vehicles at a busy toll booth outside Islamabad to administer free polio vaccination drops to children under the age of five.” The video recounts a “promise” made by Pakistan’s prime minister last month to eliminate new polio infections in the country by the end of the year and provides commentary by Shahnaz Wazir Ali, assistant to the prime minister on social affairs, and Dennis King of UNICEF Pakistan about the target, current infection rates, and ongoing eradication efforts (Tyab, 2/6).
Following an outbreak of the mosquito-borne yellow fever virus in Cameroon that has infected at least 23 people and killed at least seven people, U.N. and local officials are working to vaccinate “1.2 million people considered at high risk of contracting yellow fever, which has no cure,” the U.N. News Centre reports. “The U.N. Central Emergency Response Fund (CERF), the International Coordinating Group on Yellow Fever Provision (YF-ICG) — which includes WHO and the U.N. Children’s Fund (UNICEF) — and the public-private partnership known as the GAVI Alliance are funding the vaccination campaign,” the news service writes. In Ghana, YF-ICG is working with the European Community Humanitarian Office (ECHO) to plan a vaccination campaign after at least three cases of yellow fever have been reported in the north of the country, the U.N. News Centre notes (2/3).
“Poor-quality emergency immunization campaigns and low routine polio immunization coverage are helping the polio virus to spread in Chad, with 132 cases reported in 2011 — five times the number in 2010,” IRIN reports. “More commitment is needed across the board, especially from local health authorities, to try to get immunizations right, say aid agencies,” the news service adds.
In this AlertNet commentary, GAVI Alliance CEO Seth Berkley discusses how “public-private partnership is part of the GAVI Alliance’s formula for success that has helped countries to immunize 325 million children in our first 10 years, saving more than 5.5 million lives.” Writing last week from the World Economic Forum in Davos, Switzerland, Berkley says, “In fact, public-private partnerships are part of what brings me to Davos this week.”
This post in the U.N. Foundation’s “Shot@Life” blog examines how Honduras, “one of the poorest countries in the Western hemisphere,” has achieved “one of the highest vaccination coverage rates in the world, averaging close to 99 percent.” The blog writes, “We wanted to see firsthand how Honduras has achieved such amazing results, so last week Shot@Life traveled there with a U.S. Congressional staff delegation to learn more about their extremely effective immunization programs” and details the vaccination efforts of the rural town La CaÃ±ada (Willingham, 1/23).
In part one of a two-part blog post in USAID’s “IMPACTblog,” USAID Worldwide Polio Eradication Coordinator Ellyn Ogden reports on the “hard work and dedication of the Indian government at the national, state, district, block and panchaiyat levels” that was required for the country to have a year free of polio. “Over two million health workers, mobilizers, and volunteers have contributed to this success and deserve to be seen as heroes in their communities,” she writes (1/20). In part two of the post, Ogden recaps polio vaccination efforts and challenges, discusses the last recorded case of polio, and writes that going forward, “Guarded optimism prevails” as the country “is still at risk of importations from countries that have not yet stopped polio transmission” (1/23).
IRIN examines several factors that could be contributing to an increase in polio cases in Pakistan, “despite the launch of a National Emergency Action Plan for Polio Eradication” at the beginning of 2011. In 2010, Pakistan recorded 144 cases of polio and 192 cases in 2011, the news service reports. According to IRIN, refusals by some households to vaccinate children; “administrative laxity” and “poorly run campaigns”; and malnutrition, vitamin deficiencies, and diarrhea among children could be contributing to the campaign’s lack of success (1/23).