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Small Phase I Trial Shows HIV Vaccine Candidate Is Most Powerful To Date

Researchers at the Spanish Superior Scientific Research Council (CSIC) have successfully completed a small Phase I human clinical trial of an HIV vaccine candidate that granted 90 percent of 30 study participants an immunological response against the virus, Gizmag reports. “The MVA-B vaccine draws on the natural capabilities of the human immune system and ‘has proven to be as powerful as any other vaccine currently being studied, or even more,’ says Mariano Esteban, head researcher from CSIC’s National Biotech Centre,” the magazine writes (Borgobello, 9/28).

Maintaining Commitment Amid Promising Scientific Advances Is Necessary To Make AIDS Vaccine A Reality

In this Huffington Post opinion piece, Mitchell Warren, executive director of AVAC: Global Advocacy for HIV Prevention, examines the need for continued attention and funding for additional research for an AIDS vaccine, highlighting advancements presented at the AIDS Vaccine 2011 conference in Bangkok, Thailand earlier this month. He writes, “We don’t yet have a blueprint for an effective vaccine to roll-out. But, as presented this week in Bangkok, the complex success of the RV144 analysis, combined with a flurry of advances in understanding the development of broadly-neutralizing antibodies against HIV, show that the science of an AIDS vaccine is vibrant and vital. Now is exactly the time to maintain commitment.”

Chad Launches Three-Day Polio Vaccination Campaign

Chad’s President Idris Deby, alongside Bill Gates, co-chair of the Bill & Melinda Gates Foundation, on Friday launched a three-day polio vaccination campaign at the Friendship China-Chad hospital “as part of efforts to rid the central African nation of the infectious disease,” AlertNet reports. According to the WHO, “of the 401 declared cases of polio around the globe this year, 114 were in Chad, making it the world’s worst-hit nation,” the news service writes. Polio was presumed to be eradicated from Chad, which did not report any cases between June 2000 and July 2003, but the country has experienced a resurgence of the disease since 2003, AlertNet notes (Nako, 10/1).

Doctors' Support For MMR Vaccine Vital To Halt Measles Outbreaks In Europe, Health Official Says

“With almost 30,000 cases of measles and eight deaths from the disease recorded in the European Union so far this year, a leading health official is urging doctors to do more to ensure parents have their children vaccinated with” the measles, mumps and rubella (MMR) vaccine, Reuters reports. Marc Sprenger, director of the European Center for Disease Prevention and Control (ECDC), “said MMR vaccine coverage rates across the region are currently around 90 percent, leaving significant groups such as children or young adults unprotected,” and that “it was crucial for pediatricians and family doctors to give balanced, evidence-based information to help parents decide on vaccinations,” Reuters writes.

Polio In Pakistan Prompts India To Implement Border Crossing Vaccination Campaign

Officials in Pakistan on Monday “announced targeted, three-day anti-polio campaigns in affected areas, which include Karachi and districts in the Federally Administered Tribal Areas,” the Wall Street Journal’s “India Real Time” blog reports. According to the Global Eradication Initiative, led by the WHO, 84 cases of type 1 polio have been reported in Pakistan so far this year, nearly twice as many cases as the country had recorded by this time last year, according to the blog.

Shot@Life Campaign Aims To Expand Access To Childhood Vaccines In Developing Countries

The U.N. Foundation on Monday launched Shot@Life, “a new campaign to expand access to life-saving vaccines for children in developing countries” that “will educate, connect and empower Americans to champion vaccines as one of the most cost-effective ways to save children’s lives around the world,” according to a U.N. Foundation…

Polio Spreads From Pakistan To China; WHO Warns Of Further Spread

“Polio has broken out in China for the first time since 1999 after being imported from Pakistan, and there is a high risk of the crippling virus spreading further during the annual Haj pilgrimage, the World Health Organization said on Tuesday,” Reuters reports (9/20). Nine cases of wild poliovirus type 1 have been recorded in China’s western province of Xinjiang, which borders Pakistan, WHO spokesperson Oliver Rosenbauer said, according to Daily News and Analysis, GlobalPost notes (9/21). A genetic link has been confirmed between the virus detected in China and a strain circulating in Pakistan, according to the Associated Press/USA Today (9/20). BBC News reports that “Chinese authorities are now investigating the cases, and a mass vaccination campaign has been launched in the region” (9/20).

Researchers To Expand Malaria Vaccine Study After Initial Trial Yields Encouraging Results

Encouraged by early results of a study of an experimental malaria vaccine involving 45 children in Burkina Faso, researchers led by Pierre Druilhe at the Pasteur Institute in Paris are set to expand the clinical trial, resulting in a larger study involving 800 children in Mali, BBC News reports. The initial trial aimed “to test the safety of the vaccine but this follow up study found that children who received it had an incidence of the disease three to four times lower than children who did not,” BBC writes.

GAVI To Purchase $1 Billion In Childhood Vaccines For Distribution In 37 Of The Poorest Nations

The Geneva-based GAVI Alliance, a fund backed by governments, the World Bank, the WHO and the Bill & Melinda Gates Foundation, said in an e-mailed statement on Tuesday that it will purchase more than $1 billion in vaccines against rotavirus, pneumococcal and other diseases through deals made with GlaxoSmithKline, Pfizer Inc. and Merck & Co. to immunize children in 37 of the poorest nations, Bloomberg reports. “Wealthy nations donated $4.3 billion to purchase the vaccines as part of a plan to immunize 250 million children by 2015,” the news service notes (Bennett, 9/27).

HIV Vaccine Research Showing Promise

Recent findings on HIV vaccine research, some presented recently at the AIDS Vaccine 2011 conference in Bangkok, “show that the science of an AIDS vaccine is vibrant and vital,” Mitchell Warren, executive director of AVAC-Global Advocacy for HIV Prevention, writes in a “Science Speaks” guest blog post. “Now is exactly the…