The Center for Global Health Policy’s “Science Speaks” blog interviews tuberculosis (TB) expert Lee Reichman, founding executive director of the New Jersey Medical School Global Tuberculosis Institute, in advance of World TB Day, to be observed on March 24. According to the blog, Reichman discusses “the spread of drug-resistant TB and what he thinks are the most promising advances coming down the scientific pipeline” (Mazzotta, 3/19).
“About 900,000 cases of active tuberculosis (TB) were discovered and treated [in China] in 2011, including 423,000 infectious cases, the Ministry of Health (MOH) announced Monday at a press conference,” Xinhua reports. “Xiao Donglou, a health inspector from the MOH, said at the press conference that China improved its ability to prevent and control TB last year, focusing on HIV/TB co-infections and cases of TB among the country’s migrant population,” noting “1,701 HIV/TB co-infections were reported last year, as well as 51,682 cases of TB among the migrant population,” the news agency writes.
“[O]ften seen in the wealthy West as a disease of bygone eras,” Reuters examines rising rates of tuberculosis (TB) — drug-resistant TB in particular — among the world’s rich and poor. “[R]apidly rising rates of drug-resistant TB in some of the wealthiest cities in the world, as well as across Africa and Asia, are again making history,” Reuters writes. According to the news service, “London has been dubbed the ‘tuberculosis capital of Europe,’ and a startling recent study documenting new cases of so-called ‘totally drug-resistant’ TB in India suggests the modern-day tale of this disease could get a lot worse.”
The Bill & Melinda Gates Foundation is “to give $220 million over five years to the non-profit biotech firm Aeras to develop vaccines to fight tuberculosis [TB], a company statement said Thursday,” Agence France-Presse reports (3/15). The “grant will allow Aeras to advance several vaccine candidates into pivotal large-scale efficacy trials in South Africa and elsewhere,” South Africa’s Health-e writes (Thom, 3/15). According to AFP, Aeras “has developed six possible TB vaccines that are being tested across Africa, Asia, Europe and America” (3/15).
A joint fact sheet on the U.S.-U.K. Partnership for Global Development is available on the White House website. “Through the Partnership, we are working together to achieve better results by advancing economic growth; preventing conflict in fragile states; improving global health, particularly for girls and women; strengthening mutual accountability, transparency, and measurement of results; and mitigating the effects of climate change,” the fact sheet states, elaborating on joint efforts in each of these areas (3/14).
Largest-Ever Study Of Community-Wide TB Drug Prevention Did Not Improve TB Control In South African Mines
“After seven years of research, the world’s largest study of preventative tuberculosis (TB) therapy has found that untargeted, community-wide distribution of TB prevention drugs did not improve TB control in South African gold mines,” PlusNews reports. “Conducted among 27,000 gold-mine employees in 15 mines, the Thibela TB study tested the theory that treating an entire community with the first-line TB drug isoniazid could result in long-lasting reductions in active TB cases and TB prevalence,” the news service writes (3/9). The study found that “provid[ing] community-wide isoniazid preventive therapy (IPT)” did “not improve TB control,” according to Health-e. “However, evidence showed that there were 63 percent fewer TB cases among individuals in the program during the first nine months of the program, providing reassurance that IPT works for people who take it,” the news service notes (Thom, 3/14).
“Global health programs now teeter on the edge of disaster,” Foreign Affairs writes in this feature article, adding, “The world economic crisis and the politics of debt reduction are threatening everything from malaria control and AIDS treatment to well-baby programs and health care worker training efforts.” The article provides a historical overview of global health programming and funding. “Like it or not, the burden of reducing suffering and increasing the health of the world’s poor now falls largely on the backs of the two Washingtons,” Foreign Affairs writes, referring to politicians in Washington and the Washington state-based Bill & Melinda Gates Foundation. The article concludes, “It would be a catastrophe were the ‘age of generosity’ to end so soon after it began, leaving millions without life-sparing medicines and tools they have come to rely upon” (Garrett, 5/6).
“South Africa wants to test hundreds of thousands of miners for tuberculosis [TB] and ensure sufferers get treatment over the next year,” David Mametja, head of South African National Department of Health’s TB program, said Tuesday at a workshop organized by the Stop TB Partnership, the Associated Press/Washington Post reports. Mametja “said the government is concerned the high prevalence of the disease among miners is holding an entire region back in the fight against TB,” and that while “it may be impossible to reach the nearly 600,000 miners in South Africa in one year, even those at highest risk in the gold industry, … setting an ambitious target is a way to show ‘it’s not business as usual,'” the AP writes.
Ukraine Security Secretary Says HIV, TB Remain Threat To Nation’s Security, Encourages Cooperation With Global Fund
Speaking about two bills concerning Ukraine’s cooperation with the Global Fund to Fight AIDS, Tuberculosis and Malaria, Ukraine Secretary of National Security and Defense Council Andriy Kliuyev said “[t]he epidemics of AIDS and tuberculosis [TB] remain a threat to national security in Ukraine and require redoubled efforts to treat and prevent these diseases,” Interfax reports. Submitted to Ukraine’s parliament by the Cabinet of Ministers, the two bills “propos[e] to exempt from taxes and duties all transactions connected with the use of grants from the Global Fund to Fight AIDS, Tuberculosis and Malaria in Ukraine,” the news agency notes. “The NSDC secretary said the state should explore every avenue to minimize the sickness rate and create conditions for the treatment and prevention of dangerous diseases, adding that the grants of the Global Fund to Fight AIDS, Tuberculosis and Malaria are valuable support for Ukraine,” Interfax writes (3/3).
WHO Reports More Than 900,000 Lives Saved Because Of HIV/TB Care And Prevention Guidelines, Releases Updated Version
“An estimated 910,000 lives were saved globally in six years due to guidelines intended to ensure that people living with HIV/AIDS are protected from tuberculosis [TB], the United Nations World Health Organization (WHO) said today, releasing an updated policy on joint prevention, diagnosis and treatment of both diseases,” the U.N. News Centre reports (3/2). “The number of HIV-positive people screened for TB rose almost 12-fold, from nearly 200,000 in 2005 to more than 2.3 million in 2010, the WHO said, as it released data on the impact of its 2004 guidelines on TB and HIV,” Reuters reports (3/2).