Speaking on Saturday at a World Tuberculosis (TB) Day event, U.N. Secretary-General Ban Ki-moon “called for a global effort to diagnose and treat tuberculosis,” United Press International reports (3/24). According to the WHO, 8.8 million people contracted TB in 2010, and 1.4 million people died of the disease, primarily in low and middle-income countries, CBS News’ “Health Pop” blog notes (Castillo, 3/24). “Let us vow to end the neglect of TB and to end deaths from this disease in our lifetime,” Ban said, adding, “It is critical to support those who lack the means to respond with the care and treatment they need to enjoy healthy and productive lives. … With the right interventions, we can make a major difference,” according to the U.N. News Centre (3/24).
NGOs Release Joint Statement Calling For Governments To Increase Payments To Global Fund To Fill Gap In TB Funding
Ahead of World Tuberculosis (TB) Day on March 24, three non-governmental organizations (NGOs) released a joint statement warning that “[a] $1.7 billion funding shortfall to fight [TB] over the next five years means 3.4 million patients will go untreated and gains made against the disease will be reversed,” Reuters reports. The International HIV/AIDS Alliance, the Stop AIDS Campaign and Results UK said in the statement that the cancellation of Round 11 grants from the Global Fund to Fight AIDS, Tuberculosis and Malaria was endangering the expansion of treatment and prevention programs, the news agency notes. The statement “called on governments to scale up funding of TB, HIV and malaria programs at a G20 meeting in Mexico in June in an effort to replenish the Global Fund with $2 billion,” according to Reuters (Mollins, 3/23).
U.N. Secretary-General Ban Ki-moon on Thursday during a visit to the Institute of Respiratory Medicine in Kuala Lumpur, Malaysia, “urged countries to step up their efforts to prevent tuberculosis (TB)” and “called for ‘intensified global solidarity to ensure that the children and people of all the countries get medical support, so that they can breathe with health,'” the U.N. News Centre reports. Speaking ahead of World Tuberculosis Day on March 24, Ban said “that countries have the means to prevent unnecessary deaths, but need to implement policies that not only raise awareness about the issue but provide accessible health care to their citizens,” according to the news service. In 2011, 1.4 million people died of TB, the news service notes (2/22).
Several blog posts recently commented on the upcoming World Tuberculosis (TB) Day, commemorated on March 24. “Despite a clear legislative mandate, the U.S. Global Health Initiative (GHI) has consistently failed to live up to the goals of” the Tom Lantos and Henry J. Hyde United States Leadership Against HIV/AIDS, Tuberculosis (TB), and Malaria Reauthorization Act, a landmark legislation passed by Congress in 2008, John Fawcett, legislative director for RESULTS, writes in the Center for Global Health Policy’s “Science Speaks” blog. He continues, “Current GHI TB treatment goals are less than 60 percent of what was mandated in the Lantos-Hyde Act,” and concludes, “As the final authorized fiscal year of the Lantos-Hyde Act is debated, there’s still time to embrace its mandate: a bold effort to confront the worldâ€™s leading curable infectious killer” (Mazzotta, 3/22). “As people across the globe celebrate World TB Day this week, several groups are highlighting the fact that the current tools to prevent, test, and treat tuberculosis (TB) are greatly outdated,” Ashley Bennett, senior policy associate at the Global Health Technologies Coalition (GHTC), writes in the GHTC “Breakthroughs” blog. She commends GHTC members for their efforts to develop new technologies (3/22).
In anticipation of World Tuberculosis (TB) Day, commemorated on March 24, this Lancet editorial examines TB control and elimination efforts in 2012 and beyond. “Tuberculosis killed 1.45 million people in 2010 and about 500,000 people have drug-resistant disease,” the editorial states, adding, “Despite a woeful funding gap in 2012 of $1.7 billion, tuberculosis incidence is falling (from 9.4 million in 2009 to 8.8 million in 2010).” The editorial notes, “Ten new or repurposed tuberculosis drugs are in Phase II or III trials, which hopefully will reduce treatment times to about four months, compared with present multidrug-resistant tuberculosis regimens lasting 18-24 months,” adding, “Faster treatment will greatly improve adherence, reduce transmission, and cut costs.”
Medecins Sans Frontieres (MSF) says the spread of multidrug-resistant tuberculosis (MDR-TB) — “a form of tuberculosis that does not respond to standard treatment and can kill in a matter of months” — “is much greater than previously thought,” VOA News reports. “‘Wherever we’re looking for drug-resistant TB we’re finding it in very alarming numbers. And that suggests to us that the current statistics that are being published about the prevalence of MDR-TB are really just scratching the surface of the problem,’ said Dr. Leslie Shanks, medical director for the group,” the news service writes (DeCapua, 3/21).
In this post in USAID’s “IMPACTblog,” guest blogger Joanna Breitstein, director of communications for the TB Alliance, describes an event organized by the Critical Paths to TB Drug Regimens that took place on Monday, “heralding the launch of a new clinical trial that tests tuberculosis drugs in combination.” During the event, “Robert Clay, deputy assistant administrator in USAID’s Global Health Bureau, said that he wants researchers and those who oversee programs in countries to work more closely together,” she writes. A link to video of Clay’s comments is included in the blog (3/20).
“On Tuesday, a global alliance of researchers and scientists — led by the Stop TB Partnership, an umbrella group of health groups — unveiled a ‘blueprint’ to develop a new vaccine [against tuberculosis (TB)] that aims to disrupt transmission in hard-hit countries and communities,” the Wall Street Journal reports. “The blueprint calls for the groups to work together to test new vaccine candidates, and to coordinate fundraising for expansive and expensive human trials, representing the first comprehensive plan of the sort,” the news service writes (Wonacott, 3/20).
USAID’s website features a page dedicated to World TB Day, which will be commemorated on March 24. The page lists information on upcoming events, as well as links to several reports, such as the FY2010 Report to Congress on the Global TB Context (.pdf), stories, and features (3/19).
The TB Alliance on Monday announced it has launched a Phase II clinical trial “of a new treatment regimen for tuberculosis, including for patients with resistance to existing multi-drug programs,” Agence France-Presse reports. “The new regimen being tested could shorten required treatment to as little as four months in both patients with TB and some forms of drug-resistant TB, compared with the current six to 24 months,” the news agency writes, adding, “Costs will also be vastly reduced.” The trial “will take place at eight sites in South Africa, Tanzania, and Brazil, the alliance said,” AFP notes (Santini, 3/19).