With Africa’s “emerging position in the global order, … [a]stute African leaders are striving to ensure that this realignment delivers a new paradigm of partnership for sustainable health development — a partnership that is led by Africa, for Africans, through African-sourced solutions,” UNAIDS Executive Director Michel Sidibe writes in a Huffington Post “Impact Blog” opinion piece. The African Union is taking steps “to reduce the continent’s dependence on foreign solutions and foreign ‘aid’ while adopting and scaling up development solutions that have been proven to work in different African countries, and finding better and more sustainable approaches to financing them,” he states. “It makes a lot of sense to apply such an approach to addressing three killer diseases: AIDS, tuberculosis (TB) and malaria,” he continues, adding that “the overreliance of Africa’s AIDS response on foreign investments, foreign drugs and foreign solutions must be addressed.”
Jennifer Furin, an infectious diseases physician and medical anthropologist who specializes in the management of tuberculosis (TB) and HIV in resource-poor settings, writes in a post in the Bill & Melinda Gates Foundation’s “Impatient Optimists” blog that “when it comes to the great advancements made in global HIV and TB care, children are being left behind.” She continues, “All children with HIV and TB deserve access to diagnosis and treatment, and the death of even a single child from either one of these diseases signifies a global failure. … It is time to require that pediatric formulations of TB and HIV medications be developed.” She notes that StopTB.org will host a talk show on July 22 featuring women and young people who have been affected by TB and HIV (7/17).
GlobalPost’s “Global Pulse” blog interviews Mario Raviglione, the director of the WHO’s Stop TB Department since 2003, “about the progress and frustrations with detection and treatment of tuberculosis [TB].” Among other topics, Raviglione discusses “progress in addressing HIV-TB co-infection,” the emergence of extensively drug-resistant TB (XDR-TB), and research in diagnostics, such as the GeneXpert machine, which gives a “very quick” diagnosis of MDR-TB, according to the blog (Donnelly, 7/12).
PEPFAR “is recommending improvements to efforts to detect [tuberculosis (TB)] in settings offering health services to pregnant women, women with HIV, newborns, and children,” the Center for Global Health Policy’s “Science Speaks” blog reports. The blog outlines the recommendations of the PMTCT/Pediatric HIV Technical Working Group, which said the decision to produce guidelines for integrating TB screening into maternal and child HIV programs was based on “[r]ecent studies [that] have shown that HIV-infected pregnant women are at increased risk of transmitting both TB and HIV to their infants” (Barton, 7/11).
The widespread incidence of drug-resistant tuberculosis (TB) “calls for a new approach to TB in the developing world,” a Bloomberg editorial states. A “breakthrough test,” called Xpert MTB/RIF, “makes mass screening [for drug-resistant TB] feasible,” according to the editorial, which notes the test, developed by “California-based Cephied Inc. in collaboration with the non-profit Foundation for Innovative Diagnostics with funding from the Bill & Melinda Gates Foundation,” detects resistance to the TB drug rifampicin, provides results in two hours, and can be used without advanced laboratory facilities.
Agence France-Presse examines a rise in tuberculosis (TB) cases in Madagascar, writing, “Last year alone, 26,700 people contracted TB, according to the health ministry, a jump of more than 16 percent compared with 2009, when a military coup precipitated an economic crisis as donors suspended aid to one of the world’s poorest countries.” The news service notes, “Chronic malnutrition and poverty deepened, contributing to the spike in TB, experts say” and adds, “Even before the political crisis, Madagascar suffered one of the highest rates of malnutrition in the world.”
“A global study mapping human diseases that come from animals like tuberculosis, AIDS, bird flu or Rift Valley fever has found that just 13 such diseases are responsible for 2.4 billion cases of human illness and 2.2 million deaths a year,” Reuters reports (Kelland, 7/5). “The report, which was conducted by the International Livestock Research Institute (ILRI), the Institute of Zoology (U.K.) and the Hanoi School of Public Health in Vietnam, maps poverty, livestock-keeping and the diseases humans get from animals, and presents a ‘top 20’ list of geographical hotspots,” an ILRI press release states (7/5). The study “found that Ethiopia, Nigeria, and Tanzania, as well as India have the highest zoonotic disease burdens, with widespread illness and death,” Reuters writes.
“Johnson & Johnson [J&J] said Monday that it is seeking U.S. approval for the first new type of medicine to fight deadly tuberculosis [TB] in more than four decades,” the Associated Press reports, adding, “The experimental drug, called bedaquiline, also would be the first medicine specifically for treating multi-drug resistant tuberculosis.” According to the news service, “J&J’s Janssen Research & Development unit created the drug, which was tested in several hundred patients with multi-drug resistant tuberculosis in two mid-stage studies lasting for six months,” and “[s]ome patients were studied for about 1 1/2 years.” The news service notes, “Janssen’s head of infectious diseases, Dr. Wim Pays, said the company will also apply for approval of bedaquiline in other countries where TB is very common” (Johnson, 7/2).
GlobalPost Examines Investment In Community Care Workers In South Africa As PEPFAR Moves Toward Local Implementation Of Programming
“Nearly a decade after it came into being, the President’s Emergency Plan for AIDS Relief (PEPFAR) … is moving increasingly to support local leadership and implementation capacity” in South Africa, GlobalPost’s “Global Pulse” blog reports. “And given the South African health system’s weaknesses in the face of the magnitude of AIDS and TB, that means an investment in … lay listeners with just a few weeks of training,” who can discuss treatment and other issues with patients, the blog writes. The blog profiles Goodness Henama, “one of 22 community care workers in Wallacedene township, in the Cape Town suburb of Kraainfontein.”
In this NDTV opinion piece, Bill Gates, co-chair of the Bill & Melinda Gates Foundation, reflects on his recent trip to India, writing, “During my recent visit, I had a chance to see the latest progress on things that matter a lot to us: on eradicating polio and curtailing the spread of infectious diseases like HIV/AIDS and tuberculosis, for example.” He continues, “And I saw how India is emerging as a model and increasingly a catalyst for improvement in other developing countries,” adding, “The current situation in India is quite hopeful.”