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Tuberculosis

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Blog Examines TB In Haitian Prisons

The Center for Global Health Policy’s “Science Speaks” blog “opens a week of tuberculosis coverage with a second post from a February visit to Haiti (the first, posted Feb. 26, is here), looking at efforts by physician John May and the non-profit Health through Walls to confront the disease in…

GlobalPost, Humanitarian Agencies Examine Impact Of Childhood TB

Noting the WHO and the Global Fund to Fight AIDS, Tuberculosis and Malaria on Monday issued a joint statement calling for an additional $1.6 million a year to fight tuberculosis (TB) in low- and middle-income countries, GlobalPost’s “Global Pulse” blog examines the global impact of childhood TB, writing, “While health…

More Action Needed To Fight TB, As Drug Resistance Spreading

“As we mark World [Tuberculosis (TB)] Day on Sunday March 24, there can be no denying that TB, fueled by drug resistance, continues to pose a serious global health threat — one that must be urgently addressed,” John Lechleiter, chair, president and CEO of Eli Lilly and Company and chair…

‘Global Pulse’ Blog Examines Declining TB Incidence In Estonia

In this post in GlobalPost’s “Global Pulse” blog, journalist John Donnelly reports on tuberculosis (TB) in Estonia and how the country has significantly reduced the proportion of multi-drug resistant tuberculosis (MDR-TB) cases since 1998. He writes, “The numbers of new TB cases in Estonia were five times that of the Nordic countries in 1998, but the numbers have tumbled since then and last year Estonia had cut that in half, to 2.5 times the number.” MDR-TB still represents 22 percent of all TB cases, but several factors — including “a decision by government leaders to fully fund anti-TB efforts; banning sale of TB drugs in pharmacies in order to cut down on misuse; annual training of all TB medical staff by international experts; and the country ensured it would have enough of the scarce drugs needed to fight MDR-TB” — have helped bring down the numbers, he reports. Donnelly is reporting independently on a trip made through the Philippines, Estonia, and Peru with photographer Riccardo Venturi “at the invitation of the Japanese company Otsuka Pharmaceutical to look at the human impact of TB” (12/20).

MSF Publishes List Of Top 10 Stories Of 2011 About Access To Medicine

This Medecins Sans Frontieres (MSF) special report highlights the top 10 stories of 2011 regarding access to essential medicines, according to MSF. The list includes the findings of the HPTN 052 clinical trial, which “show that providing people with HIV treatment early not only saves their lives but can reduce the risk…

More Work Ahead In TB Drug Development, Treatment Delivery

The U.S. Food and Drug Administration’s approval of the tuberculosis (TB) drug Sirturo, also known as bedaquiline, “appears to be just the first step in an exciting renaissance for TB drug development,” Mark Harrington, executive director of Treatment Action Group (TAG), writes in the Bill & Melinda Gates Foundation’s “Impatient Optimists” blog. “Another new drug, delamanid, is currently in late clinical trials and has been submitted to the European Medicines Agency for review as a treatment for [multidrug-resistant (MDR)] TB,” he notes. Harrington concludes, “It’s an exciting time for TB treatment, but much more needs to be done and more resources are needed. We need to focus not only on the discovery and development of new drugs, but also on ensuring that news drugs are delivered to those who need them and in combinations that can prevent the emergence of new types of drug resistance” (12/28).

FDA Grants Accelerated Approval To Drug To Treat MDR-TB

“The U.S. Food and Drug Administration [on Monday] approved Johnson & Johnson’s drug to treat a form of resistant tuberculosis that is uncommon in the U.S. but growing globally,” the Wall Street Journal reports. “The drug, Sirturo, will treat patients with multidrug-resistant tuberculosis, or MDR-TB, a possibly fatal disease that affects as many as 630,000 people worldwide who can’t be cured with existing therapies alone,” the newspaper notes (Walker/Tadena, 1/2).

Zambia, Zimbabwe Address TB/HIV Co-Infection

The Center for Global Health Policy’s “Science Speaks” blog outlines efforts to fight TB/HIV co-infection in Zambia and Zimbabwe. In Zambia, a partnership among the Centre for Infectious Disease Research in Zambia with funding from PEPFAR and Zambia’s Ministry of Health began a pilot program in several prisons to identify…

TB Research Movement Formed To Drive Progress

Christian Lienhardt of the Stop TB Partnership and colleagues examine the research necessary to stop tuberculosis (TB) and introduce the TB Research Movement, which aims to “boos[t] TB research and accelerat[e] progress in TB control towards international targets,” in this PLoS Medicine article. The authors “describe the development of the Research Movement…

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