The “grand experiment” of the Affordable Medicines Facility-malaria (AMFm) — a pilot program that aims to get artemisinin-based combination therapies (ACTs) into rural areas of several African nations — “seems likely to end, its successes underrated and potential improvements not yet explored,” a Nature editorial says. In October, “an independent evaluation found that it had performed remarkably well on the main benchmarks of success, increasing the number of outlets stocking ACTs and lowering prices,” but last week “the Global Fund to Fight AIDS, Tuberculosis and Malaria decided to end the AMFm as a stand-alone program, by integrating it into the fund’s core system for awarding malaria-control grants to countries,” the editorial notes, adding, “This integration probably spells the end for AMFm, because there will be no new money for the program after the end of next year.”
Programs, Funding & Financing
The Global Fund to Fight AIDS, Tuberculosis and Malaria Board recently made several decisions that will affect the future of the organization, including appointing former U.S. Global AIDS Coordinator Ambassador Mark Dybul as executive director and adopting a new funding model, Nature reports in an article examining the history and future of the Fund. “It has been a rough couple of years for the Global Fund,” but “[l]ast week’s appointment of Mark Dybul as executive director could signal a fresh start, and has been broadly welcomed,” Nature writes (Butler, 11/22). “As [Dybul] begins his four-year term in early February 2013, current Fund General Manager Gabriel Jaramillo will transition out of his position,” PlusNews reports, noting, “That position, created to guide the Fund through reforms proposed by a 2011 high-level review panel at a time of low donor confidence, will disappear.”
UNAIDS’ new World AIDS Day report: Results, released on Tuesday, “shows that unprecedented acceleration in the AIDS response is producing results for people,” according to a UNAIDS press release. Between 2001 and 2011, “a more than 50 percent reduction in the rate of new HIV infections has been achieved across 25 low- and middle-income countries — more than half in Africa, the region most affected by HIV,” the press release states, adding, “In addition to welcome results in HIV prevention, sub-Saharan Africa has reduced AIDS-related deaths by one third in the last six years and increased the number of people on antiretroviral treatment by 59 percent in the last two years alone.” According to the press release, “The area where perhaps most progress is being made is in reducing new HIV infections in children,” and the number of AIDS-related deaths has dropped because of increased access to antiretroviral treatment.
Emergency Obstetric Care Reduced Maternal Mortality Rates Up To 74% In Two African Projects, MSF Reports
According to a new briefing paper (.pdf) from Medecins Sans Frontieres (MSF), access to emergency obstetric care, including ambulance service, could help save the lives of up to three quarters of women who might otherwise die in childbirth, AlertNet reports (Batha, 11/19). In two projects, one in Kabezi, Burundi, and the other in Bo, Sierra Leone, MSF showed “that the introduction of an ambulance referral system together with the provision of emergency obstetric services can significantly reduce the risk of women dying from pregnancy related complications,” according to an MSF press release. The services, which cost between $2 and $4 per person annually, are offered 24 hours a day, seven days a week, and are free of charge, the press release notes (11/19). The projects “cut maternal mortality rates by an estimated 74 percent in Kabezi and 61 percent in Bo,” Reuters writes, adding, “The charity hopes its model could serve as an example for donors, governments and other aid agencies considering investing in emergency obstetric care in countries with high maternal mortality rates” (11/19).
In a statement released on Monday, WHO Director-General Margaret Chan said “[s]everal recent media articles are creating misinformation and confusion in the public health arena” by “erroneously suggesting that, in working to reduce non-communicable diseases (NCDs) such as cardiovascular diseases, cancers, chronic respiratory diseases and diabetes, WHO receives funding from the food and beverage industry,” the U.N. News Centre reports. Referring to an October 19 article by Reuters suggesting the Pan American Health Organization (PAHO) had accepted money from the industry and a similar November 1 piece by Mother Jones, Chan said, “The allegations in these articles are wrong,” and she added, “When WHO works with the private sector, the organization takes all possible measures to ensure its work to develop policy and guidelines is protected from industry influence,” the news service notes (11/19).
A “key problem” in reaching the goal of polio elimination “may well be that organizers of the global anti-polio initiative, and of other global health programs, are not listening to the people they want to help — or to each other,” Thomas Abraham, an associate professor in the Journalism and Media Studies Center at the University of Hong Kong, writes in a New York Times opinion piece. “As a result, in many communities targeted by [polio immunization] programs, people perceive a gulf between global programs like polio eradication and more immediate local health needs,” he continues, adding, “It is cold comfort to save a child from polio if the child later succumbs to malaria or diarrhea from dirty drinking water.”
Following the appointment of Ambassador Mark Dybul to be the next executive director of the Global Fund to Fight AIDS, Tuberculosis and Malaria, as well as the Global Fund Board’s adoption of a new funding model, German Development Minister Dirk Niebel released his government’s next payment to the Global Fund in the amount of 100 million euros ($128 million), according to a press release from the German Federal Ministry for Economic Cooperation and Development. With the release of funds, the total contribution of the German government to the Global Fund in 2012 is 200 million euros ($256 million), the press release notes (11/16).
“Medical researchers in the Republic of the Congo (Congo-Brazzaville) have been empowered to set their own research priorities through a funding mechanism backed by a French oil company, according to scientists speaking at the second European and Developing Countries Clinical Trials Partnership (EDCTP), in South Africa this month,” SciDev.Net reports. “In 2011, the Congolese Foundation for Medical Research signed an agreement with TOTAL, stipulating that the energy giant would fund specific research activities and pay salaries,” which “enabled the foundation to set its own research priorities — a break with the usual funding constraints whereby researchers’ priorities are dictated by foreign funding agencies,” the news service writes.
The focus of the Uniting to Combat Neglected Tropical Diseases: Translating the London Declaration into Action conference, which took place November 16-18 in Washington, D.C., was “how we can work together to put the right systems in place and implement the change needed” to control or eliminate neglected tropical diseases (NTDs) by 2020, Simon Bush, director of NTDs at Sightsavers, writes in the Huffington Post U.K.’s “Impact” blog. Sponsored by the World Bank and the Bill & Melinda Gates Foundation, the conference brought together pharmaceutical company executives, non-governmental organization (NGO) representatives, academics, government officials, and representatives of the World Bank, WHO and other groups, Bush says.
Noting the Global Fund to Fight AIDS, Tuberculosis and Malaria met last week to discuss progress in fighting the three diseases, Lucy Chesire, executive director and secretary to the board of the TB ACTION Group, interviews Lucica Ditiu, executive secretary of the Stop TB Partnership, about the global response to tuberculosis (TB) in the Huffington Post’s “The Big Push” blog. In the blog, Ditiu summarizes the state of the global TB response, discusses the emergence of multidrug-resistant TB (MDR-TB), and addresses the Global Fund’s role in the response to TB and the future of these efforts. “The Global Fund has an ambitious strategy that includes important milestones for anti-TB efforts,” Ditiu said, adding, “The international community must find a way to fund that strategy and to ensure that resources are allocated in a way that achieves the greatest good for the greatest number of people,” according to the blog (11/16).