The first-ever results from a dengue virus vaccine clinical trial aimed at showing effectiveness “provide signals rather than definitive answers, and a mixture of both promise and unresolved challenges,” Orin Levine, executive director of the International Vaccine Access Center, and Ciro de Quadros, executive vice president of the Sabin Vaccine Institute, write in the Huffington Post “Impact” blog. “To date, these represent the most promising indications that a safe, effective vaccine to prevent dengue is technically feasible,” they continue, adding, “At the same time, the results on protection were inconclusive, somewhat inconsistent with the measured immune responses and uneven across the four strains included in the vaccine.”
Private Sector Involvement
“Severe droughts, rising grain prices and food shortages — the latest headlines are an urgent call for action,” and “it is time to step up our response,” Suma Chakrabarti, president of the European Bank for Reconstruction and Development (EBRD), and Jose Graziano da Silva, director-general of the U.N. Food and Agriculture Organization (FAO), write in a Wall Street Journal opinion piece. On September 13, the EBRD and FAO will convene the Private Sector for Food Security Conference in Istanbul, Turkey, “the largest and most important gathering of companies and decision-makers in agribusiness from the Caspian and Black seas to the Mediterranean … [to] discuss the key role of the private sector in feeding the world,” they note. “The simple truth is that the world needs more food, and that means more production,” they state, adding, “The private sector can be the main engine of such growth.”
As the BRIC countries — Brazil, Russia, India, and China — invest more in innovations in health technologies and other areas, “many are looking to these countries to correct the global health research and development (R&D) imbalance that leaves the poor without needed products such as an improved tuberculosis (TB) vaccine or tests to help diagnose patients in remote rural settings,” David de Ferranti, president of Results for Development Institute (R4D), writes in the Huffington Post Blog. Writing that “India, which has already played such an important role in manufacturing affordable antiretroviral drugs, vaccines, and other essential health commodities for developing countries,” de Ferranti asks whether India “is … ready to play a leading role in health R&D?”
In an opinion piece in the Guardian’s “Comment is Free” blog, Dean Baker, co-director of the Center for Economic and Policy Research, discusses potential policies contained within the “Trans-Pacific Partnership Agreement (TPP), a pact that the United States is negotiating with Australia, Canada, Japan and eight other countries in the Pacific region.” However, “[a]t this point, it’s not really possible to discuss the merits of the TPP since the governments are keeping the proposed text a secret from the public,” he says. Noting “[a] few items that have been leaked give us some insight as to the direction of this pact,” he discusses how the “pharmaceutical industry is … likely to be a big gainer” from the TPP if the pact includes “stronger and longer patent protection and also increased use of ‘data exclusivity.'”
“When you’re dealing with a global public health crisis, having an international presence isn’t just advisable — it is imperative,” Margaret McGlynn, president and CEO of the International AIDS Vaccine Initiative (IAVI), writes in this post in USAID’s “Impact” blog, adding, “That’s why [IAVI], in partnership with USAID, has worked diligently over the past several years to establish itself as a truly global non-profit partner.” She continues, “IAVI has created an enviable network of research centers in sub-Saharan Africa dedicated to assessing novel AIDS vaccine candidates in clinical trials and conducting supporting epidemiological studies on HIV,” and writes that these “partnerships have made meaningful contributions to the research capacity of many developing countries — a capability that is now helping local researchers tackle other diseases” (8/13).
“A global alliance to protect the world’s people from toxic lead, chromium, mercury, pesticides and other pollution has been formed by the World Bank, Asian Development Bank, U.N. agencies, donor countries, foundations and non-government experts in July,” freelance journalist Ben Barber reports in this post in Huffington Post’s “Green” blog. “The Global Alliance for Health and Pollution (GAHP) aims to work together to protect the health of over one hundred million people in poor countries who are at risk from toxic pollution,” Barber writes, adding, “The group will work with governments to clean-up toxic hotspots where children, especially, are being poisoned. It could also respond to emergencies such as a recent lead poisoning outbreak in Nigeria that killed hundreds of children” (8/10).
In a post in the Guardian’s “Sustainable Business” blog, Lisa Herman, managing director of the global health practice area at consulting firm FSG, and Mike Stamp, a senior consultant with FSG, discuss “a new guide for companies on how to participate in global action on women and children’s health” recently launched at the London Family Planning Summit. “The guide, co-authored by social impact consultants FSG and sponsored by the Innovation Working Group in support of the global Every Woman, Every Child effort, sets out concrete opportunities for companies from many different industries to contribute to improving women and children’s health,” they write.
Diagnostics company Cepheid on Monday signed deals with PEPFAR, USAID, UNITAID, and the Bill & Melinda Gates Foundation to immediately reduce the price of its Xpert MTB/RIF test kit for its GeneXpert tuberculosis (TB) diagnostic system in 145 countries, Reuters reports. “The agreements will see the test sold for $9.98, down from its current price of $16.86 per test,” the news service writes, adding, “Cepheid said the Bill & Melinda Gates Foundation will make an initial payment of $3.5 million to make the test immediately available at the lower price” (Ail, 8/6).
Extreme weather is forcing grain and meat prices to rise, and food production will have to increase about 60 percent over the next 40 years to meet a growing world population, but “there are solutions to these daunting problems,” Catherine Bertini, former director of the U.N. World Food Programme and the 2003 World Food Prize laureate, and Dan Glickman, former secretary of agriculture, write in a Politico opinion piece. The authors, co-chairs of the Chicago Council on Global Affairs’ Global Agricultural Development Initiative, say that in order to address these issues, “we should increase support for the agricultural researchers, in the U.S. and around the world, who are developing remarkable new drought and flood tolerant crop varieties”; make better use of arable land, especially in Africa; provide “farmers access to improved seeds, pesticides and fertilizers to boost productivity”; improve post-harvest infrastructure, including storage facilities; and “equip those working in agriculture, especially women, with the know-how to use newer technologies.”
In this post in the Center for Strategic & International Studies’ (CSIS) “Smart Global Health” blog, Rhonda Zygocki, executive vice president of policy and planning at Chevron, responds to questions about Chevron’s presence at the XIX International AIDS Conference (AIDS 2012) in Washington, D.C., last week, writing that such questions “give me an opportunity to talk about the critical role everyone plays in the global fight against this epidemic, including Chevron, as well as the ways collaborative partnerships will lead to the elimination of AIDS.” She highlights the company’s HIV prevention efforts, including a pledge last year of $20 million to the U.N.’s mission to eliminate mother-to-child HIV transmission by 2015, and continues, “Individuals, non-profit organizations, medical practitioners, representatives of governments, and companies from the private sector joined together in Washington, D.C., with the same vision: to create an HIV-free generation and eliminate AIDS around the world” (8/1).