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Disease Diagnosis/Detection

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News Outlets Examine International Efforts To Contain H1N1

A WHO official on Tuesday backed the Afghan government’s decision to declare H1N1 (swine flu) a health emergency, forcing the closure of all schools in the country for three weeks in an effort to contain the virus, IRIN reports. H1N1 has reportedly infected over 300 people, resulting in two deaths.

MDR-TB, XDR-TB More Widespread Than Previously Believed, Study Shows

In a study published on Wednesday in the Lancet, researchers from the Centers for Disease Control and Prevention found that “[a]mong 1,278 patients who were resistant to two or more first-line tuberculosis drugs in Estonia, Latvia, Peru, Philippines, Russia, South Africa, South Korea and Thailand, 43.7 percent showed resistance to at least one second-line drug,” which “suggest[s] the deadly disease may become ‘virtually untreatable,'” according to the study, Bloomberg Businessweek reports (Kitamura/Narayan, 8/29). “In about a fifth of cases, they found resistance to at least one second-line injectable [versus oral] drug,” according to Reuters, which states “[t]his ranged from two percent in the Philippines to 47 percent in Latvia.” Overall, 6.7 percent of patients had extensively drug-resistant TB (XDR-TB), meaning patients are resistant to the first-line drugs isoniazid and rifampicin as well as drugs in the fluoroquinolone antibiotic class and a second-line injectable antibiotic, Reuters adds, noting “[r]ates in South Korea, at 15.2 percent, and Russia at 11.3 percent, were more than twice the WHO’s global estimate of 5.4 percent at that time” (Kelland, 8/30).

India's Contribution To Global Health R&D Needs Domestic, International Support

As the BRIC countries — Brazil, Russia, India, and China — invest more in innovations in health technologies and other areas, “many are looking to these countries to correct the global health research and development (R&D) imbalance that leaves the poor without needed products such as an improved tuberculosis (TB) vaccine or tests to help diagnose patients in remote rural settings,” David de Ferranti, president of Results for Development Institute (R4D), writes in the Huffington Post Blog. Writing that “India, which has already played such an important role in manufacturing affordable antiretroviral drugs, vaccines, and other essential health commodities for developing countries,” de Ferranti asks whether India “is … ready to play a leading role in health R&D?”

White House Issues First-Ever National Biosurveillance Strategy

In an article on the U.S. Department of Defense webpage, the American Forces Press Service reports on the first U.S. National Strategy for Biosurveillance, issued by the White House “to quickly detect a range of global health and security hazards.” According to the article, “the Defense Department has a running start in implementing the new plan, a senior defense official said,” and “many of the activities described in the strategy are ongoing at DOD.” “So much of what we’re doing is integrating the efforts and working hard on the overlap between global security and global health, in what [President Barack Obama] refers to as global health security,” said Andrew Weber, assistant secretary of defense for nuclear, chemical and biological defense programs, the news service writes (Pellerin, 8/22).

New Disease Causes AIDS-Like Symptoms But Not Spread Through Virus

“Researchers have identified a mysterious new disease that has left scores of people in Asia and some in the United States with AIDS-like symptoms even though they are not infected with HIV,” the Associated Press reports. “This is another kind of acquired immune deficiency that is not inherited and occurs in adults, but doesn’t spread the way AIDS does through a virus, said Dr. Sarah Browne, a scientist at the National Institute of Allergy and Infectious Diseases,” who “helped lead the study with researchers in Thailand and Taiwan where most of the cases have been found since 2004,” according to the news service. “Researchers are calling this new disease an ‘adult-onset’ immunodeficiency syndrome because it develops later in life and they don’t know why or how,” AP writes, adding, “The fact that nearly all the patients so far have been Asian or Asian-born people living elsewhere suggests that genetic factors and something in the environment such as an infection may trigger the disease, researchers conclude” (Marchione, 8/22).

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