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Research Suggests Number Of Dengue Cases Three Times Higher Than Current WHO Estimate

“Around 390 million people are infected each year with dengue fever — the world’s fastest-spreading tropical disease — more than triple the current estimate by the World Health Organization, experts said on Sunday,” Reuters reports. The findings, published by researchers from the University of Oxford and the Wellcome Trust in the…

Dengue Incidence In Brazil Increased In 2013 Over Last Year

“Health authorities in Brazil say there has been a steep rise in the confirmed cases of dengue fever this year,” with “more than 200,000 people … infected in the first seven weeks of 2013 compared to 70,000 in the same period last year, official figures suggest,” BBC News reports. “Health Minister Alexandre…

BMJ Examines Why India’s Dengue Epidemic Continues To Grow

This BMJ feature examines why India’s dengue epidemic continues to grow worse each year, stating, “In the past decade, according to the National Vector Borne Disease Control Programme (NVBDCP), the number of cases has escalated steadily from 3,306 in 2001 to 47,209 in 2012,” and “[d]eaths have risen from 53 in 2001…

WHO Warns Of Dengue’s Spread, Says Progress Made Against NTDs In New Report

“Dengue is the world’s fastest-spreading tropical disease and represents a ‘pandemic threat,’ infecting an estimated 50 million people across all continents, the World Health Organization (WHO) said on Wednesday,” Reuters reports. In a statement, the WHO said dengue “register[ed] a 30-fold increase in disease incidence over the past 50 years,” and the…

Growing Number Of Dengue Cases In India Increases Risk Of Disease Spreading Worldwide, Experts Warn

“An epidemic of dengue fever in India is fostering a growing sense of alarm even as government officials here have publicly refused to acknowledge the scope of a problem that experts say is threatening hundreds of millions of people, not just in India but around the world,” the New York Times reports. Dengue is endemic in half of the world’s countries and continuing to spread, experts say, according to the newspaper. In India’s capital, New Delhi, “where areas of standing water contribute to the epidemic’s growth, hospitals are overrun and feverish patients are sharing beds and languishing in hallways,” the newspaper writes. With officials citing 30,002 cases of dengue in India through October, “a 59 percent jump from the 18,860 recorded for all of 2011,” several experts say the true number of infections in the country is in the tens of millions, the New York Times notes.

Financial Times Features Special Report On NTDs

The Financial Times has published a special report (.pdf) on neglected tropical diseases (NTDs) featuring 10 articles examining issues including prevention, research, and treatment.

Dengue Vaccine Initiative Launches Redesigned Website, New Blog

The Global Network for Neglected Tropical Diseases’ “End the Neglect” blog reports that the Dengue Vaccine Initiative has launched a redesigned website, including a new blog that “will include regular posts about the disease, dengue in the news, the work of DVI and the development of a dengue vaccine” (9/17).

Number Of Recorded Dengue Cases Up 36% Over Last Year In Costa Rica

“A total of 8,480 people have been affected by dengue fever in Costa Rica” so far this year, representing an increase of 36 percent, or 2,230 more cases than during the same period last year, according to a Ministry of Health report, Xinhua News reports. “Among all the cases so far, only nine people were affected by hemorrhagic dengue fever, which is a more serious and sometimes mortal type of dengue, the report added,” the news service writes (9/17). Health authorities are urging people to eliminate possible sources of reproduction for mosquitoes, including disposing of old tires, according to a health ministry press release (9/11).

Clinical Trial Results Signal 'Promise, Unresolved Challenges' In Finding Effective Dengue Vaccine

The first-ever results from a dengue virus vaccine clinical trial aimed at showing effectiveness “provide signals rather than definitive answers, and a mixture of both promise and unresolved challenges,” Orin Levine, executive director of the International Vaccine Access Center, and Ciro de Quadros, executive vice president of the Sabin Vaccine Institute, write in the Huffington Post “Impact” blog. “To date, these represent the most promising indications that a safe, effective vaccine to prevent dengue is technically feasible,” they continue, adding, “At the same time, the results on protection were inconclusive, somewhat inconsistent with the measured immune responses and uneven across the four strains included in the vaccine.”

Leading Dengue Fever Vaccine Candidate 30% Effective In First Large Clinical Trial

“The leading candidate to become the world’s first vaccine against dengue fever was only 30 percent effective in its first large clinical trial, dealing at least a temporary setback to efforts to control a disease that threatens half the world’s population,” the New York Times reports. “Still, the study marked a milestone in the 70-year quest to develop such a vaccine, demonstrating that a safe and effective inoculation against dengue is feasible, researchers reported in a paper published online Monday in the Lancet,” the newspaper adds (Pollack, 9/10). “Tested among just over 4,000 children in rural Thailand who were badly exposed to the mosquito-borne fever, the vaccine had no side effects but only worked against three out of the four dengue strains,” Agence France-Presse writes (9/10).